Risk of aortic aneurysm and dissection in patients with autosomal ...
Keywords: autosomal-dominant polycystic kidney disease, aortic aneurysm, aortic dissection, population-based cohort study. INTRODUCTION. Autosomal-dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, with the incidence ranging from 1/400 to 1/1000 in United States [1, 2]. The ADPKD is genetically heterogeneous ...
Vascular Complications in Autosomal Dominant Polycystic Kidney Disease ...
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 (located on chromosome 16p13.3) or PKD2 (located on chromosome 4q22.1). PKD1 and PKD2 encode two integral membrane proteins, polycystin-1 (PC1) and polycystin-2 (PC2), respectively.
Aortic dissection in patients with autosomal dominant polycystic kidney ...
Aortic dissection (AD) is the most common life-threatening disease involving the aorta. It is rarely associated with systemic disorders such as Autosomal Dominant Polycystic Kidney Disease (ADPKD), a genetic syndrome characterized by cystic degeneration of kidneys, possible presence of cysts in othe …
Autosomal dominant polycystic kidney disease and the heart …
Jun 1, 2017 · Autosomal dominant polycystic kidney disease (ADPKD) has numerous systemic manifestations and complications. This article gives an overview of hypertension, cardiac complications, and intracranial aneurysms in ADPKD, their pathophysiology, and recent developments in their management.
Vertebral artery dissection in patients with autosomal dominant ...
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal cystic disease, and it is associated with various extrarenal manifestations, including vascular complications, such as intracranial aneurysms, and aortic root dilatation and aneurysms.
Arterial dissections in autosomal dominant polycystic kidney disease ...
A computed tomographic angiogram (CTA) showed the presence of polycystic kidney and liver disease and confirmed the existence of synchronous dissection of the left subclavian artery and the abdominal aorta beginning below the renal arteries and extending to the bifurcation and left common iliac artery.
Polycystic Kidney Disease, Autosomal Dominant
Jan 10, 2002 · Autosomal dominant polycystic kidney disease (ADPKD) is generally a late-onset multisystem disorder characterized by bilateral kidney cysts, liver cysts, and an increased risk of intracranial aneurysms.
Thoracic aortic dissection in a patient with autosomal dominant ...
Oct 6, 2016 · Autosomal dominant polycystic kidney disease is one of the most common hereditary diseases, and frequently has well defined extrarenal manifestations. Very few cases of aortic aneurysms associated with this disorder are described in literature.
Aortic Dissection in Familial Patients with Autosomal Dominant ...
Mar 3, 2021 · Autosomal dominant polycystic kidney disease (ADPKD) is the most common congenital kidney disease. However, reports on occasional cases of aortic dissection in PKD familial patients remain scarce. Herein, we describe rare aortic dissection cases in PKD familial patients (i.e., mother and daughter) and our successful treatment experience.
Aortic dissection in patients with autosomal dominant polycystic kidney ...
Dec 5, 2014 · It is rarely associated with systemic disorders such as Autosomal Dominant Polycystic Kidney Disease (ADPKD), a genetic syndrome characterized by cystic degeneration of kidneys, possible presence of cysts in other organs and extra-renal manifestations, including cardiovascular disorders.