α-Glucosidase - Wikipedia
In this sense, "alpha-glucosidase" can encompass a wide range of enzyme activitiess, differing by the linkage of their terminal (1→3, 1→4, or 1→6), the specific identity of their substrate (sucrose, maltose, or starch), among other aspects.
Alpha-Glucosidase - an overview | ScienceDirect Topics
Alpha-glucosidase, a brush border enzyme that hydrolyzes starch and disaccharides to release glucose for absorption into the enterocyte, is another enzyme potentially involved in whey-mediated glucose lowering.
Alpha-Glucosidase - an overview | ScienceDirect Topics
Alpha-glucosidase is an enzyme that plays an important role in the absorption of glucose in the gastrointestinal tract. Inhibition of this enzyme activity can reduce blood glucose levels, preventing postprandial hyperglycemia in patients with type 2 diabetes mellitus.7.
Alpha-Glucosidase Inhibitory Assay-Screened Isolation and …
Alpha-glucosidase inhibitors (such as acarbose) slow the digestion of carbohydrates by reversible and competitive inhibition. The postprandial glucose rise in the blood is dose-related and, therefore, decreased due to the down-regulation of direct glucose absorption [2].
An overview on the role of bioactive α-glucosidase inhibitors in ...
In enzyme kinetics study, it was revealed that BA binds to α-glucosidase by competing with pNPG (p-nitrophenol-αD-glucopyranoside), a substrate used for the assay of α-glucosidase activity. Moreover, BA can also efficiently bind with α-glucosidase-pNPG complex to …
Alpha Glucosidase Inhibitors - StatPearls - NCBI Bookshelf
Feb 28, 2024 · Alpha-glucosidase inhibitors inhibit the absorption of carbohydrates from the small intestine. They competitively inhibit enzymes that convert complex nonabsorbable carbohydrates into simple absorbable carbohydrates. These enzymes …
Glucosidases - Wikipedia
Alpha-glucosidases are enzymes involved in breaking down complex carbohydrates such as starch and glycogen into their monomers. [ 2 ] They catalyze the cleavage of individual glucosyl residues from various glycoconjugates including alpha- or beta-linked polymers of glucose.
α-Glucosidases and α-1,4-glucan lyases: structures, functions, and ...
α-Glucosidases (AGases) and α-1,4-glucan lyases (GLases) catalyze the degradation of α-glucosidic linkages at the non-reducing ends of substrates to release α-glucose and anhydrofructose, respectively. The AGases belong to glycoside hydrolase (GH) families 13 and 31, and the GLases belong to GH31 and share the same structural fold with GH31 AGases.
Alpha glucosidase inhibition activity of phenolic fraction from
Jul 8, 2020 · The purified fraction named ‘fraction-14’ had shown significant inhibition of yeast alpha glucosidase enzyme activity (IC 50 = 2.4 ± 0.4 μg/mL) when compared to anti-diabetic drug acarbose (IC 50 = 2450 ± 24 μg/mL).
Emerging strategies for the activity assay and inhibitor screening …
Alpha-glucosidase has been considered as the main target enzyme in the prevention and treatment of type 2 diabetes, and the inhibition of alpha-glucosidase activity can control postprandial blood glucose levels of diabetics and keep blood glucose levels normal.
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