Pathology Outlines - Hyperplastic polyp
Nov 18, 2021 · Comparison with adjacent nonlesional large intestinal mucosa may facilitate the recognition of goblet cell rich variant and reduce the risk of underdiagnosis, since the serrations are more subtle than in the microvesicular type (Histopathology 2021;78:634)
Hyperplastic polyp - patholines.org
Dec 10, 2023 · There are two main types of hyperplastic polyps, which have genetic differences, as well as different histologic structure, but no significant differences clinically: A microvesicular mucin-rich type; A goblet cell-rich type; Mucin-rich type
Hyperplastic polyp in colon: Causes, treatment, and outlook
Aug 2, 2023 · According to a 2020 article, there are three main types of hyperplastic polyps. They are: Mucin-poor hyperplastic polyps: This serrated polyp contains small cells without mucus....
Microvesicular hyperplastic polyp and sessile serrated lesion of …
HPs show two main growth patterns: microvesicular and goblet cell-rich. The former type shows morphological and molecular similarities (eg, BRAF mutations) to the more recently described sessile serrated lesion (SSL). In this review, we debate whether these lesions represent a biological spectrum or separate entities.
Crypts composed of large number of goblet cells with surface serrations. On the left side colon, mucosal herniation in hyperplastic polyp is a known diagnostic pitfall, the basal crypt architecture may be distorted due to prolapse type changes. Recommended surveillance interval for colonoscopy is 3 years.
Mar 23, 2023 · Microvesicular Hyperplasic Polyp (MVHP): Fine apical vacuoles in epithelial cells at surface. Stellate, frilly, lumina in cross section. Goblet cell-rich Hyperplastic Polyp (GCHP): Subtle! Taller and wider crypts (than normal), with slight surface serrations. Cross-sections round. Serrated Polyps Usually large (≥1 cm) sessile, right-sided lesions
Molecular characteristics of colorectal hyperplastic polyp …
Goblet-rich hyperplastic polyps (GRHP). Numerous goblet cells with no atypia/mitosis or vesiculation (a) and c) HEx10), (b) and d) H&Ex20). The mucin-poor HPP group was with the least number of patients after re-evaluation.
Serrated lesions of the colon and rectum: Emergent …
Nov 9, 2020 · Histopathologic features of serrated lesions. (a) Goblet cell-rich hyperplastic polyp. The crypts show the typical sawtooth architecture, which is more evident superficially and contain a large number of goblet cells. (Hematoxylin and eosin stain, 200× magnification.) (b) …
Colorectal Goblet Cell Rich Hyperplastic Polyp - National Center …
A serrated hyperplastic polyp that arises from the colon and rectum. It is characterized by the presence of goblet cells and the absence of microvacuolated columnar cells. There is no evidence of epithelial atypia or dysplasia.
A morphologic reappraisal of endoscopically but not …
Goblet cell--rich hyperplastic polyps (GCRHP) are morphologically subtle compared to microvesicular hyperplastic polyps (MVHP) and are believed to be the most commonly unrecognized serrated polyp, though this has not been systematically studied.