However, Yost did add that one day of irregularly eating can impact people with chronic health conditions. Echoing Heffron, she said that people with chronic diseases such as heart failure, high blood pressure or diabetes especially need to follow their doctor’s dietary recommendations, including during the holiday season.

Should I tell relatives I'm taking a weight loss drug? That’s up to you. Eating habits are on display with Thanksgiving meal. And if you’re concerned about getting comments or

“I love Thanksgiving for the pumpkin pie — it's such a low-sugar dessert that it tends to be fine for your blood sugar,” Bensley tells PEOPLE. “Chocolate is okay, but just try to do it with your meal to keep that blood sugar stable.”

Dr. Caroline Apovian says you can still enjoy the holidays and festive meals while you're taking GLP-1 medications if you follow some simple rules.

This may be the first Thanksgiving for millions of Americans who are on GLP-1 agonists like Ozempic, Zepbound or Wegovy.

For most, Thanksgiving is all about the big meal. The turkey, which may be roasted, smoked, brined or deep fried, side dishes, followed by pies (yes, multiple — pecan? pumpkin? apple?) typically amount to a buffet of choices.

Holidays bring time with family, cultural celebrations and rest, but Thanksgiving, often centralized around food, may also ignite anxiety for some people.