SAN DIEGO -- Results from a small single-center study showed that treatment with a gene therapy involving the use of ...

Among these sensors, we further focused on the spatiotemporal dynamics of Rab10 and Rab4 activity during sLTP. We found that postsynaptic stimulation leads to the persistent inactivation of Rab10 and ...

To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, they added cyclosporin (CsH) to increase transduction by inhibiting lentiviral restriction factors.

Breakthrough in Delivering Chimeric Bait Receptors to Immune Cells Accelerates Development LONDON, UK / ACCESSWIRE / December ...

Lentiviral transduction of producer cells, followed by expansion of transduced cells, amplified the fraction of producer cells with a single barcode-capsid variant pair. The barcoded eVLP capsid ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

Advances in genetic cell modifications are performed routinely in research laboratories, but clinical translation requires ...

Conclusions RNAScope, RT-ddPCR, and dPLA can successfully detect lentiviral RNA and EGFP from multiple tissue sources. These methods could prove useful for testing therapeutic vector transduction ...