The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

How will the Eagles fare in a playoff atmosphere? They passed a test on Sunday with perhaps their most impressive win. And ...

The San Francisco 49ers plan to place running backs Christian McCaffrey and Jordan Mason on injured reserve after suffering ...

The Buffalo Bills clinched their record fifth consecutive AFC East title Sunday night after defeating the 49ers 35-10 on ...

Christian McCaffrey and Jordan Mason both landed on IR after the 49ers lost to the Bills in Week 13. Isaac Guerendo will now take over the backfield.

One week after Buffalo Bills quarterback Josh Allen proposed to Hailee Steinfeld, he shared what it was like to be back on ...

As the San Francisco 49ers confirmed Christian McCaffrey suffered a likely season-ending injury, his backup, Jordan Mason, landed on IR with a high-ankle sprain.

After U.S. travelers battled through harsh weekend weather to reach home following the Thanksgiving holiday, forecasters say ...

First it was Christian McCaffrey and now it is Jordan Mason who the 49ers won't have for the remainder of the season.

Jennifer Lee Chan highlights potential external options the San Francisco 49ers could consider after injuries to Christian ...

The San Francisco 49ers entered this season with lofty aspirations. For the most part, their hopes have been dashed -- and ...