Safety and Efficacy of Osimertinib in Patients With Non–Small-Cell Lung Cancer and Uncommon Tumoral Epidermal Growth Factor Receptor Mutations: A Systematic Review and Single-Arm Meta-Analysis Patient ...

Type D—the D stands for “distressed”—is described as a combination of being inhibited in social situations and tending to experience negative emotions. The concept of Type D is distinct ...

Despite all these published in vitro, in vivo and even preliminary clinical studies showing desirable features of HDACIs as a potential therapeutic agent, so far, to the best of the authors ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Patients with type 2 and type 1 diabetes (T2D ...

This fundamental article significantly advances our understanding of FGF signalling, and in particular, highlights the complex modifications affecting this pathway. The evidence for the authors' ...

This study unveils important data describing cell states of olfactory ensheathing cells, and how these cell states may relate to repair after spinal cord injury. The framework used for characterizing ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Human pluripotent stem cells (hPSCs) exist in ...

Objective: To evaluate relative expression of genes with the potential to translate environmental stimuli into long-term alterations in the brain, namely early growth response (EGR)1, EGR3, and ...

Chen et al.(82) applied the cocktail CH, VPA, RepSox, FSK, SP600125, GO6983, and Y-27632 to achieve Nestin+, Pax6+, and Sox2+ iNPCs transdifferentiated from stem cells from the apical papilla (SCAPs) ...

Klamath County is exploring the forefront of a new era of government efficiency through artificial intelligence (AI).