Uncontrolled series using pneumatic compression devices (PCDs) have been shown to reduce symptoms of RLS. We sought to assess the efficacy of PCDs as a nonpharmacologic treatment for RLS.

The final cohort was comprised of 35 subjects, 21 randomized to therapeutic PCDs, and 14 randomized to subtherapeutic "sham" devices. No subjects reported a need to initiate or escalate medical ...