Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including ...

Research utilizing AI tool AlphaFold has revealed a new protein complex that initiates the fertilization process between ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are ...

A protein has many identities and one of them depends on the arrangement of its amino acids in the three dimensions of space — in other words, its 3D structure. And scientists have spent decades ...

elegans, reveal the ketone body β-hydroxybutyrate interacts directly with misfolded proteins, altering their solubility and structure so they can be cleared from the brain through the process of ...

e.g., a receptor protein. DeepFPlearn + is an extension of deepFPlearn[2], which uses binary fingerprints to represent the molecule's structure computationally. The DFPL package requires a particular ...