Several observations from preclinical and short-term clinical studies support a role for sildenafil in the treatment ... in 'systolic' heart failure to the population with 'diastolic' heart ...

Heart failure with normal systolic function has been equated to diastolic heart failure (DHF ... of DHF is often made by exclusion, and treatment is empirical and unsatisfactory because of ...

Doctors call this diastolic heart failure or heart failure with preserved ... "There is much more to those drugs than weight loss alone." More information: Milton Packer et al, Tirzepatide for ...

Aldosterone-receptor blocking drugs can slow the progression of ... in patients with mild symptoms or underlying diastolic heart failure, and the use of aldosterone-receptor antagonists in ...

The test of tirzepatide, brand named Zepbound, included 731 patients with diastolic heart failure and obesity who were followed for two years. Advertisement "This class of drugs continue to show ...

"This class of drugs continue to show benefits far ... heart failure and preserved heart function." Obesity and Heart Failure Diastolic heart failure, also known as heart failure with preserved ...

However, medications that improve survival rates ... Heart failure with preserved ejection fraction (HFpEF), also called ...

“This is the first trial that tested the effect of any medication on major heart failure outcomes in patients with HFpEF and obesity.” Within the study population, 731 patients had diastolic ...

A widely used heart failure medication called sacubitril/valsartan was associated with a lower risk of heart damage compared to placebo among high-risk cancer patients being treated with ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...