In a significant medical feat, Indian scientists have developed the first-in-human gene therapy using lentiviral vectors for ...
Haemophilia is a severe bleeding disorder caused by the deficiency of clotting Factor VIII, leading to spontaneous internal ...
In the groundbreaking study the researchers observed an annualised zero bleeding rate in all the five subjects enrolled with ...
Current treatments require frequent Factor VIII replacement therapy, which faces challenges such as high costs, venous access ...
SAN DIEGO -- Results from a small single-center study showed that treatment with a gene therapy involving the use of ...
BHUBANESWAR: In a significant medical breakthrough, India's first human gene therapy with a lentiviral vector for severe haemophilia-A has been found to be succ ...
India has successfully conducted its first in-human gene therapy for hemophilia A, with patients experiencing no bleeding ...
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In particular, patients who had fewer than 10 annual vaso-occlusive events before the gene therapy were more likely to have ...
The companies all use modified versions of the same lentiviral vectors used in ex vivo CAR ... the capability really of transforming in vivo gene therapy in general as we move forward and get ...
Among these sensors, we further focused on the spatiotemporal dynamics of Rab10 and Rab4 activity during sLTP. We found that postsynaptic stimulation leads to the persistent inactivation of Rab10 and ...