Diastolic dysfunction increasingly is recognized as an important cause of congestive heart failure (CHF). In this study, Mayo Clinic researchers surveyed a random sample of 2042 adults (age ...

Cardiac diastolic dysfunction (CDD), ultimately leading to heart failure ... In this study, 12-month-old female mice were ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

In addition, when systolic and diastolic images are subtracted pixel–by–pixel, the resulting 'regional EF' images from occluded mice clearly show apical dysfunction relative to normal control ...

Diastolic heart failure is common in the elderly, particularly women. Previous studies on the value of brain natriuretic peptide in diastolic dysfunction have been largely limited to male subjects.

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284 , discusses the effect of long-term administration of green tea catechins ...

More information: Jordan S.F. Chan et al, Growth differentiation factor 15 alleviates diastolic dysfunction in mice with ...

To address this unmet clinical need, we have identified a mouse model of arthritis, K/BxN F1 progeny, which recapitulates the specific diastolic dysfunction of RA patients; this is the first mouse ...

Within the last decade, we discovered that the fibroblasts isolated from the old mouse heart have an altered phenotype ... which directly leads to diastolic dysfunction. Because of inflammatory ...