Unfortunately, despite its emerging importance, no simple or universally accepted definition of DHF has yet been found. Previous studies have used a broad and heterogeneous variety of diagnostic ...

Chronic heart failure (CHF) is associated with frequent ... dysfunction and those with preserved LV systolic function or diastolic dysfunction. The management of HTN in patients with CHF is ...

Systolic heart failure, which is when the ventricles cannot contract (pump blood) well during a heartbeat. Diastolic heart failure, which is when the ventricles cannot relax and fill with blood ...

Heart failure with preserved ejection fraction ... who were subsequently diagnosed with HFpEF did not have guideline-defined diastolic dysfunction. Robust discrimination for HFpEF was seen ...

In infants with cardiomyopathy-associated chronic HF, baseline LVEF of less than 40% and β blocker use indicate a decreased chance of LVEF normalization.

Two widely publicized clinical trials provide data demonstrating survival benefits with spironolactone and eplerenone in chronic and ... or underlying diastolic heart failure, and the use of ...

A total of 731 patients with diastolic heart failure and a body mass index (BMI) of 30 or above were randomized to receive injections of either tirzepatide or a harmless placebo. The researchers ...

A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows. The test of tirzepatide, brand named Zepbound, included ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

Researchers suggest an application to FDA may be made within the next 12 months, requesting approval to carry out a human clinical trial with the gene therapy.

He had had 2 previous admissions —in May, 1960, and April, 1962 — with edema, exertional dyspnea and orthopnea, ascribed to congestive heart failure ... and an apical diastolic gallop, as ...