Research on ALS has increased dramatically in the last 30 years, [1] with a number of etiologic factors explored ( Table 1). Ninety percent to 95% of cases of ALS are sporadic (SALS), occurring ...
Long-term treatment with the cell therapy NurOwn (debamestrocel) was found to significantly extend survival in people with amyotrophic lateral sclerosis (ALS) when compared with a matched control ...
A database integrating long-term respiratory data with natural history data from people with amyotrophic lateral sclerosis (ALS) has been made available to scientists globally, with the hopes of ...
[49] Glutamate excitotoxicity in HD has been hypothesized ... He is the Director of the Robert Packard Center for ALS Research at Johns Hopkins, and Director of the MDA/ALS Clinic, and Vice ...
The Overall Survival study demonstrated substantially extended survival in people living with ALS who received the investigational treatment. The second analysis identified the importance of ...
Mammalian excitatory amino acid transporters (EAATs) are responsible for clearing the neurotransmitter glutamate from the synaptic cleft (for review see Grewer et al., 2014; Takahashi et al., 2015; ...