A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284 , discusses the effect of long-term administration of green tea catechins ...

Cardiac diastolic dysfunction (CDD), ultimately leading to heart failure ... In this study, 12-month-old female mice were ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to ...

We followed distinct mouse models of major HFpEF comorbidities for 2.5 ... Hyperglycemia accelerated diastolic dysfunction and HFpEF onset associated with reduced arterial flow and left ventricular ...

It should be appreciated that clinical heart failure with preserved systolic function (diastolic heart failure) can be caused by heterogeneous pathophysiologic conditions. Hypertrophic ...

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Twenty-four patients (60%) who were subsequently diagnosed with HFpEF did not have guideline-defined diastolic dysfunction. Robust discrimination for HFpEF was seen for left atrial emptying ...