A recent study published in Biophysics Reports has shed light on the crucial role of β-adrenergic receptors (βARs) in ...

Major beta blocker mortality trials in chronic heart failure: a critical review. Heart. 1999;82(suppl 4):IV14 IV22. Altered adrenergic receptor sensitivity due to polymorphic variation.

We further report the functional characterization in flies of one family of these genes, encoding for nicotinic acetylcholine receptor (nAchR) subunits. We find that nAchR signaling in enterocytes of ...

Standard pharmacological β-adrenergic receptor antagonism prolongs ... thus restoring α2-receptor signaling, decreasing circulating catecholamine levels, and enhancing cardiac function after ...

Receptor endocytosis is important for signal activation, transduction, and deactivation. However, how a receptor interprets conflicting signals to adjust cellular output is not clearly understood.

Beta-blockers are effective at decreasing the morbidity and mortality associated with CHF. They lower the risk of all-cause mortality, cardiovascular mortality, sudden death, and death from ...