SAN DIEGO -- Results from a small single-center study showed that treatment with a gene therapy involving the use of ...

To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, they added cyclosporin (CsH) to increase transduction by inhibiting lentiviral restriction factors.

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...

ESO-T01 is the first in vivo BCMA CAR-T candidate to reach the clinical stageEarly clinical data are expected in second half of ...

Lentiviral transduction of producer cells, followed by expansion of transduced cells, amplified the fraction of producer cells with a single barcode-capsid variant pair. The barcoded eVLP capsid ...

Aubourg and colleagues achieved a transduction efficiency of ∼15% in hematopoietic stem cells with their lentiviral vector, compared with the 0.01% recorded previously with murine γ-retroviral ...

Breakthrough in Delivering Chimeric Bait Receptors to Immune Cells Accelerates Development LONDON, UK / ACCESSWIRE / December ...

More recently, the Vector Development Laboratory merged with our group, and we have expanded our services to offer AAV, first-generation adenovirus (FGAd), helper-dependent adenovirus (HDAd), ...

These luciferase expressing cell lines were derived from parental lines by transduction with lentiviral vector encoding firefly luciferase gene (luc2) under control of EF-1 alpha promoter. These cell ...