Cancer cells impair monocyte-mediated T-cell activation by disrupting inflammatory pathways in the tumor microenvironment.

B cells have a fundamental role ... not only as precursors of antibody-producing cells, but also as important regulators of the T-cell activation process through their participation in antigen ...

SLAM is constitutively expressed on immature thymocytes, memory T cells and a proportion of B cells, and can be induced on T and B cells following activation ... Vav-2 and is dependent on the ...

Inflammatory processes are the body’s defence against local damage and disease. Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with ...

A study in mice offers evidence that inhibiting EZH2 can enhance lymphoma immunogenicity and overcome CAR-T cell therapy resistance.

The main populations of lymphocytes are B cells, T cells and natural killer ... METTL1 drives B cell activation via the tRNA m 7 G modification-dependent translation of BCR signaling and that ...

The infusions can be repeated after 6-12 months, at a point when B cells start rebounding or ... can induce demyelination within the PNS T-cell-dependent B-cell activation leads to production ...