Medically reviewed by Susan Bard, MD There are a few reasons why it may take time to heal a big pimple. It's normal for some ...

Isotretinoin is indicated for nodular acne or severe acne that is unresponsive to conventional therapies. The usual dose is 0.5 to 1.0 mg/kg/day for 20 weeks, or a cumulative dose of 120 mg/kg.

Occasionally, intralesional injection or drainage of cysts and nodules will be helpful in resolving inflammation. Acne conglobata (AC) is the correct answer. This is a severe form of acne that is ...