Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the laboratory or clinic. In this episode, Charlene ...

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...

In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell mitosis to access the nucleus. As a consequence, lentviruses are able to replicate within non ...