The adeno-associated viral (AAV) vectors have not been exploited extensively partly due to inability to generate high titer helper free recombinant viruses. Furthermore, the size of the transgene ...
In the original lentivirus vectors described by Naldini et al (Naldini et al., 1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is ...
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