Pathologically high levels of extracellular glutamate can cause excitotoxicity, when postsynaptic receptors ... amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), Alzheimer’s disease, ...
or FDA-approved drugs that modulate glutamate neurotransmission have shown therapeutic potential in CNS maladies such as epilepsy and other seizure disorders, bothersome tinnitus, the lethal ...
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