The Hoosiers jumped out to an early lead when quarterback Kurtis Rouke handed the ball off to Ty Son Lawton, who scored the game's first touchdown. However, this lead was short-lived, as the Buckeyes' defense quickly took control.

The Hoosiers have been the season's biggest surprise team and are 10-0 for the first time in school history. However, IU has not played a ranked team. The Hoosiers are playing in just their second-ever AP top-5 matchup. Ohio State has played in 46.