Tisch, 43, the Harvard-educated scion of a wealthy New York family, has worked for the city for 16 years, holding leadership roles in several agencies. As sanitation commissioner, she became TikTok famous when she declared in 2022, “The rats don’t run the city, we do.”

New York City Mayor Eric Adams on Wednesday appointed Jessica Tisch as commissioner of the New York City Police Department, the second woman to lead the department in 179 years.