Anderson is a city in and the county seat of Anderson County, South Carolina, United States. The population was 28,106 at the 2020 cens…Anderson is a city in and the county seat of Anderson County, South Carolina, United States. The population was 28,106 at the 2020 census, making it the 16th-most populous city in South Carolina. It is one of the principal cities in the Greenville-Anderson-Greer, SC Metropolitan Statistical Area, which had an estimated population of 975,480 in 2023. It is included in the larger Greenville-Spartanburg-Anderson, SC Combined Statistical Area, which had an estimated population of 1,590,636 in 2023. It is just off Interstate 85 and is 120 miles from Atlanta and 140 miles from Charlotte. Anderson is the smallest of the three primary cities that make up the Upstate region, and is nicknamed the "Electric City" and the "Friendliest City in South Carolina".
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