Palmira is a city and municipality in southwestern Colombia in the Valle del Cauca Department, located about 27 kilometres east from Cali, the d…Palmira is a city and municipality in southwestern Colombia in the Valle del Cauca Department, located about 27 kilometres east from Cali, the department's capital and main city in the South of Colombia. Palmira is the second largest city in the Valle del Cauca, behind Cali.