Association with proteins outside the TLR family also increases diversity (for example, TLR4 recognizes LPS in association with proteins called MD2 and CD14). TLRs 1, 2, 4, 5, and 6 are located ...
TLR antagonists are being investigated for the treatment of inflammatory diseases. Examples here include the inhibition of TLR7 and TLR9 in systemic lupus erythematosus, inhibition of TLR4 in ...
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