Objective To address clinical uncertainties about the effectiveness and safety of long-term antibiotic therapy for preventing recurrent urinary tract infections (UTIs) in older adults. Design ...

Objectives To identify different patterns (trajectories) of childhood urinary incontinence and examine which patterns are associated with bladder and bowel symptoms in adolescence. Design Prospective ...

Objective To investigate the relationship between temperature extremes and daily number of deaths in Jinan, a temperate city in northern China. Methods Data ondaily number of deaths and meteorological ...

Objectives The evolution of multimorbidity describes the continuum from a healthy status to the development of a single disease and further progression to multimorbidity with additional diseases. We ...

Objectives Patient-reported outcome measures (PROMs) collected in clinical trials should be administered in a standardised way across sites and routinely screened for avoidable missing data in order ...

Objective To investigate how smoking status is recorded in UK primary care; to evaluate whether appropriate multiple imputation (MI) of smoking status yields results consistent with health surveys.

1 Radboud University Medical Centre, Scientific Institute for Quality of Healthcare, Nijmegen, The Netherlands 2 HAN, University of Applied Sciences Nijmegen, Institute of Health Studies, Nijmegen, ...

Objectives Hospital-acquired bloodstream infections are known to increase the risk of death and prolong hospital stay, but precise estimates of these two important outcomes from well-designed studies ...

2 Department of Business Information Systems, University College Cork, Cork, Ireland 3 Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland 4 Mercy University Hospital, ...

Objective To assess the evidence for the claim probiotics can correct dysbiosis of the normal microbiota resulting from disease or disruptive events. Setting Systematic review of published clinical ...

Protocol: Addition of prophylactic compression garments to standard care to prevent irreversible lower limb lymphoedema after gynaeco-oncological therapy (Gynolymph): protocol for a randomised ...

Objective To describe the clinimetric validation of the I-DECIDED tool for peripheral intravenous catheter assessment and decision-making. Design and setting I-DECIDED is an eight-step tool derived ...