Kansas City Chiefs quarterback Patrick Mahomes didn’t run out of bounds on his 33-yard run against the San Francisco 49ers ...

Like Dallas, the Niners have struggled through some of the season’s early portion due to various key injuries.

San Francisco 49ers' Deebo Samuel left Week 7 due to an illness, but head coach Kyle Shanahan has offered a huge update on ...

The San Francisco 49ers have officially placed wide receiver Brandon Aiyuk on Injured Reserve after he suffered a ...

The San Francisco 49ers are making their first moves after confirming that Brandon Aiyuk tore his ACL and MCL this past ...

The San Francisco 49ers have a long list of players missing from their first Week 8 practice. Headlining that list are two of ...

The wide receiver position has taken a significant hit for the San Francisco 49ers. Brandon Aiyuk will miss the remainder of the season with a torn ACL and MCL.

The 49ers' Nick Bosa expects the Dallas Cowboys to attempt a more run-oriented approach when they visit Levi's Stadium ...

The San Francisco 49ers were reportedly interested in reuniting with wide receiver Kendrick Bourne during the offseason as ...

Brandon Aiyuk has been placed on injured reserve, dealing a major blow to the 49ers as they navigate key injuries.

George Kittle seems on track for another All-Pro campaign. However, the San Francisco 49ers tight end did not make it out of ...

San Francisco 49ers trade rumors are heating up again after Brandon Aiyuk has been ruled out with a season-ending ACL injury.