SciELO25d
Advances in the development of new vaccines for tuberculosis and Brazil’s role in the effort forward the end TB strategy
Tuberculosis (TB) continues to be the world’s leading killer of infectious diseases. Despite global efforts to gradually reduce the number of annual deaths and the incidence of this disease, the ...
ahajournals.org25d
Vascular Endothelial Cells and Innate Immunity
From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...
Frontiers14d
Gut-brain axis and neurodegeneration: mechanisms and therapeutic potentials
This paper reviews the effects of gut microbiota in regulating neurodegenerative diseases through controlling gut-brain axis. Specific microbial populations and their metabolites (short-chain fatty ...
Frontiers20d
Emerging functions of lycopene in the management of digestive premalignant lesions
Once toll-like receptor 4 (TLR-4) is activated, Tir domain-containing adaptor inducing interferon-beta (TRIF) can bind to TRAF6, then activate a series of kinases, promote entry of activated nuclear ...
gut.bmj6d
Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease
Binding of microbial products to pathogen pattern receptors promotes liver inflammation and injury. Toll-like receptor (TLR)-4 is the cell receptor for LPS and changes in its signalling contribute to ...