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Seahawks (+3, 42.5) and Dolphins vs. 49ers (+1.5, 44.5). As for those wide lines, Green Bay is a 14-point home favorite over the Saints in the Week 16 NFL betting odds, while Buffalo is favored by ...

Patriots has Buffalo favored by 14 points in the largest of the Week 16 NFL lines and one of the biggest ... its Week 16 NFL predictions: the Jets (+3, 47) cover at home versus the Rams in well ...

The line for this game opened at Bucs -4.5 but has ... In those games, he averaged 16.3 carries for 107.5 YPG. On Sunday, he faces a Cowboys run defense that has allowed the fourth-most rushing ...

Week 16 of the ... under this line in three of his last five games. Collins has missed some time, but when he's on the field, he has been phenomenal, averaging 8.6 targets and 94.3 receiving ...

Expect Green Bay's running game to dominate behind an offensive line that ranks seventh in run ... The Saints are 3-14 ATS in prime-time games over the last five seasons, the worst record in ...

Philadelphia is favored by four points in the Week 16 NFL odds, up a half-point from the opener, while another divisional contest in Colts vs. Titans has Indianapolis favored by 3.5 points. If you're ...