TLR antagonists are being investigated for the treatment of inflammatory diseases. Examples here include the inhibition of TLR7 and TLR9 in systemic lupus erythematosus, inhibition of TLR4 in ...

In a recent Perspective in Nature Immunology 1, Blander and Medzhitov explored the function of Toll-like receptor (TLR) signaling in controlling the maturation of phagosomes in macrophages and ...

A diverse workforce brings a range of skills, perspectives, and experiences that drive innovation and problem-solving, which in turn can lead to enhanced decision-making and improved business ...

LAS VEGAS, Nov. 5, 2024 /PRNewswire/ -- The VIVA Foundation, a not-for-profit organization dedicated to advancing the field of vascular medicine and intervention through education and research, ...

The Army G-8 is the Army’s lead for matching available resources to the defense strategy and the Army plan. We accomplish this through participation in the Office of the Secretary of Defense ...

In 2023, Vinuesa received the Lupus Insight Prize for the discovery that gain-of-function mutations in the gene that encodes the toll-like receptor 7 (TLR7) cause human lupus. 18 Her team identified a ...

Volkswagen Jetta – 8.8 / 10 Best German Luxury Small Cars BMW 3 Series – 8.6 / 10 Audi A4 – 8.5 / 10 BMW 3 Series (hatchback) ...

However, the Mariners simply cannot stop trying. With arguably the best starting rotation in the sport, all it will take is ...

IND cleared by FDA and dosing in the Phase 1 clinical trial initiated, with data expected in the first half of 2025Sanofi ...

Objectives Sjögren’s disease (SD) is an autoimmune disease affecting the exocrine glands that is associated with autoantibodies against Ro60/SS-A, anti-Ro52/TRIM21, La/SS-B and others. We examined the ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...