Benghazi is the second-most-populous city in Libya as well as the largest city in Cyrenaica, with an estimated population of 1,207,250 in 2020. …Benghazi is the second-most-populous city in Libya as well as the largest city in Cyrenaica, with an estimated population of 1,207,250 in 2020. Located on the Gulf of Sidra in the Mediterranean, Benghazi is also a major seaport.